Hereditary genetic diseases for donor or partner compatibility
The panel consists of 430 genes associated with more than 400 hereditary diseases including all the recessive diseases panel, X-Linked Carrier and many recessive genes associated with infertility. As the diseases are recessive and carrying one or more of the disease-causing alleles is not unusual. The test panel is best used to screen for partner or donor (Sperm/egg) compatibility. By screening both parents, the test can ensure that no two copies of the same disease-causing gene are present. This is especially useful for parents when selecting donors for fertility treatment.
The panel is regularly updated according to the newest recommendations and knowledge obtained in the field of genetic diseases.
How are the relevant conditions and genes selected?
It currently includes >1400 genes associated with more than 750 conditions. The number of conditions is smaller than the number of genes, since some genetic conditions can be caused by changes in more than one gene.
The selection of genes investigated in and is recommended by clinical geneticists, genetic scientists, genetic pathologists, and genetic counselors, and the list is reviewed regularly.
The selection of genes is based on the following criteria:
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The gene is known to cause a recessive genetic condition
- The condition is early onset
- The condition has a serious impact on a person’s quality of life and/or is life-limiting
- Screening of the gene is possible using currently available technology
GET TESTED BEFORE:
- Trying to get pregnant.
- Starting an assisted fertilization treatment.
- Starting treatment with donor eggs or sperm. Both patient and donor can be healthy carriers of diseases with a genetic mutation in the same gene.
How to do it?
